Current clinical trials in CKD

November 2, 2024

The Chronic Kidney Disease Solution™ By Shelly Manning It is an eBook that includes the most popular methods to care and manage kidney diseases by following the information provided in it. This easily readable eBook covers up various important topics like what is chronic kidney disease, how it is caused, how it can be diagnosed, tissue damages caused by chronic inflammation, how your condition is affected by gut biome, choices for powerful lifestyle and chronic kidney disease with natural tools etc.


Current clinical trials in CKD

There are several current clinical trials focused on chronic kidney disease (CKD) aimed at exploring various treatment approaches and therapies. Here are some notable examples:

  1. EASi-KIDNEY Trial: This trial is investigating the combination of vicadrostat (a selective aldosterone synthase inhibitor) and empagliflozin (an SGLT2 inhibitor) to see if it reduces the risk of CKD progression, heart failure hospitalizations, or cardiovascular death compared to empagliflozin alone. It’s expected to involve approximately 4,000 participants over three to four years, with results anticipated by 2028​

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  2. Stem Cell Therapy Trials: Various trials at the Mayo Clinic are evaluating the safety and effectiveness of mesenchymal stem cell therapies in CKD patients. These studies aim to assess how well stem cells derived from adipose tissue can help repair kidney damage and improve function​

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  3. ISCHEMIA-CKD Trial: This study focuses on patients with stable ischemic heart disease and advanced CKD, comparing outcomes between a routine invasive strategy (which includes cardiac catheterization) and a conservative management approach. This trial is crucial as it looks to determine the best management strategy for these high-risk patients​

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  4. Evaluation of Lixivaptan: Another trial is investigating the pharmacokinetics and safety of lixivaptan in patients with autosomal dominant polycystic kidney disease (ADPKD) who also have CKD​

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These trials reflect a growing emphasis on innovative treatments and strategies to manage CKD more effectively. You can find detailed information on these and other trials through clinical trial registries or institutional websites like the Mayo Clinic and other research institutions.

The Chronic Kidney Disease Solution™ By Shelly Manning It is an eBook that includes the most popular methods to care and manage kidney diseases by following the information provided in it. This easily readable eBook covers up various important topics like what is chronic kidney disease, how it is caused, how it can be diagnosed, tissue damages caused by chronic inflammation, how your condition is affected by gut biome, choices for powerful lifestyle and chronic kidney disease with natural tools etc.