What is the main cause of Chronic Kidney Disease?

March 8, 2024

The Chronic Kidney Disease Solution™ By Shelly Manning It is an eBook that includes the most popular methods to care and manage kidney diseases by following the information provided in it. This easily readable eBook covers up various important topics like what is chronic kidney disease, how it is caused, how it can be diagnosed, tissue damages caused by chronic inflammation, how your condition is affected by gut biome, choices for powerful lifestyle and chronic kidney disease with natural tools etc.


Chronic kidney disease (CKD) can have multiple causes, and the primary cause often depends on individual factors such as medical history, lifestyle, and genetic predisposition. However, some common underlying conditions and risk factors can contribute to the development of CKD:

  1. Diabetes: Diabetes mellitus, particularly type 2 diabetes, is one of the leading causes of CKD. High blood sugar levels over time can damage the small blood vessels in the kidneys, leading to impaired kidney function and CKD. Diabetic nephropathy is a specific type of kidney damage caused by diabetes.
  2. Hypertension (High Blood Pressure): Uncontrolled hypertension is another significant risk factor for CKD. High blood pressure can damage the blood vessels in the kidneys and increase the risk of kidney disease over time.
  3. Glomerulonephritis: Glomerulonephritis refers to inflammation of the glomeruli, which are the tiny filters in the kidneys responsible for filtering waste and excess fluid from the blood. Various underlying conditions and infections can cause glomerulonephritis and lead to CKD if left untreated.
  4. Polycystic Kidney Disease (PKD): Polycystic kidney disease is an inherited disorder characterized by the growth of cysts in the kidneys. These cysts can gradually enlarge and impair kidney function, leading to CKD and eventual kidney failure.
  5. Autoimmune Diseases: Certain autoimmune diseases, such as lupus nephritis and IgA nephropathy (also known as Berger’s disease), can cause inflammation and damage to the kidneys, leading to CKD.
  6. Kidney Stones and Obstructions: Chronic obstruction of the urinary tract due to conditions such as kidney stones, enlarged prostate, or urinary tract abnormalities can impair kidney function and lead to CKD over time.
  7. Recurrent Kidney Infections: Chronic or recurrent kidney infections, particularly if left untreated, can cause scarring and damage to the kidneys, leading to CKD.
  8. Certain Medications: Long-term use of certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), certain antibiotics, and some medications used to treat hypertension and other conditions, can potentially cause kidney damage and contribute to CKD.
  9. Aging: Aging itself is a risk factor for CKD, as kidney function naturally declines with age. However, the rate of decline can be accelerated by underlying health conditions and lifestyle factors.
  10. Other Risk Factors: Additional risk factors for CKD include obesity, smoking, family history of kidney disease, and certain ethnic backgrounds (e.g., African American, Hispanic, Indigenous Australian).

It’s important to note that CKD often progresses slowly and may not cause noticeable symptoms in the early stages. Regular monitoring of kidney function through blood and urine tests is essential for early detection and management of CKD, particularly in individuals with risk factors for the condition. If you have concerns about your kidney health or are at risk for CKD, it’s essential to consult a healthcare professional for proper evaluation and management.

The Chronic Kidney Disease Solution™ By Shelly Manning It is an eBook that includes the most popular methods to care and manage kidney diseases by following the information provided in it. This easily readable eBook covers up various important topics like what is chronic kidney disease, how it is caused, how it can be diagnosed, tissue damages caused by chronic inflammation, how your condition is affected by gut biome, choices for powerful lifestyle and chronic kidney disease with natural tools etc.